Hypoglycaemic Mortality in Diabetes

By: Philip E. Cryer, MD & Simon R. Heller, DM, FRCP|Date: Tuesday 12 September 2017| Categories: Diabetes, Hypoglycaemia, Mortality|

Abstract

Iatrogenic hypoglycaemia is the limiting factor in the glycaemic management of diabetes, particularly with insulin. That hypoglycaemia can kill experimental animals has been known since the discovery of insulin. There are now numerous reports of deaths of patients with diabetes associated with hypoglycaemia. Since hypoglycaemia can kill, and hypoglycaemia at the time of death has been documented by continuous glucose monitoring in a patient with diabetes, it is reasonable to conclude that these are causal associations.